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Endoscopic balloon dilatation for Crohn's strictures of the gastrointestinal tract is feasible
John Gásdal Karstensen1, Jakob Hendel, Peter Vilmann
1Department of Surgical Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark. johngkarstensen@hotmail.com
Insights
Endoscopic balloon dilatation is a safe alternative to surgery for Crohn´s disease strictures, avoiding surgery in most patients. However, recurrence rates necessitate further procedure optimization.
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Inflammatory Bowel Disease
Background:
- Crohn's disease often leads to gastrointestinal strictures, frequently requiring surgical intervention.
- Endoscopic balloon dilatation has emerged as a viable non-surgical alternative for managing these strictures.
- This study reports on the clinical experience with endoscopic dilatation for Crohn's disease-related gastrointestinal strictures.
Purpose of the Study:
- To evaluate the safety and efficacy of endoscopic balloon dilatation for gastrointestinal strictures in Crohn's disease patients.
- To assess the rate of recurrence and need for surgery following endoscopic dilatation.
- To determine the complication rate associated with the procedure.
Main Methods:
- A retrospective analysis of 23 patients with Crohn's disease and obstructive gastrointestinal symptoms was conducted.
- Patients underwent endoscopic dilatation between January 2005 and February 2011.
- Pre-procedure evaluation included barium small-bowel follow-through, MRI, and/or endoscopy.
Main Results:
- Endoscopic dilatation was performed in 19 of 23 patients (83%).
- During a mean follow-up of 21 months, 74% of patients experienced relapse, and 26% required surgery.
- A total of 54 dilatations were performed with a low complication rate of 1.9% (one perforation).
Conclusions:
- Endoscopic dilatation appears to be a safe procedure for managing obstructive gastrointestinal symptoms in Crohn's disease.
- The procedure successfully avoided surgery in approximately 75% of patients during the follow-up period.
- Further optimization is required to reduce the recurrence rate of strictures after endoscopic dilatation.
Introduction:
Despite optimized medical treatment, Crohn´s disease can cause gastrointestinal (GI) strictures, which requires surgical intervention. Lately, endoscopic balloon dilatation has been established as an alternative to surgery. In the following, we report our experiences with endoscopic dilatation of strictures in the gastrointestinal tract caused by Crohn´s disease.
Material And Methods:
From January 2005 to February 2011, 23 patients with Crohn´s disease were referred for endoscopic dilatation. Based on data derived from this cohort, a retrospective analysis was made. Patients with Crohn´s disease, obstructive GI symptoms and known bowel strictures were included. Their mean age was 39 years (20-59 years) and 65% were female. Prior to the procedure, all patients had been evaluated by barium small-bowel follow through, abdominal magnetic resonance imaging and/or endoscopy.
Results:
Dilatation was performed in 19/23 (83%) patients. During a mean follow-up period of 21 months (range 1-47 months), relapse was observed in 14/19 patients (74%). Five patients (26%) were referred to surgery due to complications (n = 1) or multiple relapses (n = 4). A total of 54 endoscopic dilatations were performed during the study period. Only one complication (perforation) was experienced, which resulted in a complication rate of 1.9%.
Conclusion:
Endoscopic dilatation in patients with Crohn´s disease with obstructive GI symptoms seems safe. In three out of four patients, surgery was avoided during a mean follow-up of two years. Further optimisation of the procedure is needed to lower the rate of recurrence.
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