[A sero-epidemiological study on HBV infection in a farm]

A seroepidemiological study on HBV infection was carried out in a farm with a population of 777. HBsAg, anti-HBs and anti-HBc were tested with SPRIA; HBeAg and anti-HBe with ELISA and HBV DNA with spot hybridization. The results showed that: 1. in HBeAg negative individuals, the positive rate of HBV DNA was 9.33%, as a result, the infectivity of HBsAg carriers could not be estimated accurately with HBeAg examination only; 2. among the total HBV infected individuals, the positive rate of HBsAg of the males was significantly higher than that of the females (51.38% vs 38.89%, P less than 0.005), indicating the difference of response to HBV between males and females; 3. in anti-HBs positive individuals, 42.53% were anti-HBs positive alone, of which, 78.72% had evidence of HBV infection four years before the examination, indicating that the majority of persons who had anti-HBs alone were specifically responsive to HBV.