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Updated: May 20, 2026
11:53
Crystallization of Membrane Proteins in Lipidic Mesophases
Published on: March 28, 2011
A 1:1 cocrystal of baicalein with nicotinamide
Michał Sowa1, Katarzyna Ślepokura, Ewa Matczak-Jon
1Department of Chemistry, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Abstract:
Cocrystallization of baicalein with nicotinamide yields a 1:1 cocrystal [systematic name: pyridine-3-carboxamide-5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one (1/1)], C(6)H(6)N(2)O·C(15)H(10)O(5). The asymmetric unit contains one baicalein and one nicotinamide molecule, both in neutral forms. Molecules in the cocrystal form column motifs stabilized by an array of intermolecular hydrogen bonds.
