Related Experiment Video
Updated: May 20, 2026

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
Published on: February 23, 2018
Annual influenza vaccination: offering protection beyond infection
Kelly C Rogers1, Juliet P Wallace, Stephan L Foster
1Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee, Memphis, TN 38163, USA. kcrogers@uthsc.edu
Insights
Annual inactivated influenza vaccination may reduce cardiovascular disease (CVD) risks. Despite evidence, vaccination rates remain low in CVD patients, highlighting a need for improved public health strategies for heart health.
Area of Science:
- Public Health
- Cardiology
- Infectious Diseases
Background:
- Cardiovascular disease (CVD) is the leading global cause of mortality.
- Influenza vaccination is associated with reduced CVD morbidity and mortality.
- Vaccination rates in CVD patients are below Healthy People 2020 goals.
Purpose of the Study:
- To review the importance of influenza vaccination in CVD patients.
- To summarize literature on seasonal influenza vaccination and CVD incidence.
- To examine the impact of vaccination on coronary artery disease and stroke.
Main Methods:
- Literature review of existing studies.
- Analysis of data on influenza vaccination and cardiovascular outcomes.
- Examination of epidemiological trends in CVD and influenza immunization.
Main Results:
- Evidence suggests inactivated influenza vaccine reduces CVD-related complications.
- Consistent underachievement of vaccination targets in the CVD population.
- Further research needed to fully elucidate the protective role of vaccination.
Conclusions:
- Seasonal influenza vaccination is crucial for managing cardiovascular disease.
- Improving immunization rates in CVD patients is a public health priority.
- Vaccination strategies can mitigate risks of coronary artery disease and stroke.
Abstract:
Cardiovascular disease (CVD), the leading cause of death in the world, is largely preventable. An increasing amount of evidence suggests that annual vaccination with inactivated influenza vaccine reduces morbidity and mortality associated with CVD; however, immunization rates in patients with CVD fall consistently below the goals established by Healthy People 2020. This review outlines the importance of vaccination and summarizes the available literature on the role of seasonal influenza vaccination and the incidence of coronary artery disease and stroke.
Related Concept Videos
Vaccinations
Influenza
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Vaccines
Active versus Passive Immunity
Active Immunity
Active immunity refers to the resistance one develops...
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...

