Related Experiment Video
Updated: May 20, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
[Development and validation of the Tonsillectomy Outcome Inventory 14]
T Skevas1, C Klingmann, P K Plinkert
1HNO-Klinik, Krankenanstalt "Mutterhaus der Borromäerinnen", Akademisches Lehrkrankenhaus der Universität Mainz, Trier, Deutschland. theodoros.skevas@mutterhaus.de
A new questionnaire, the Tonsillectomy Outcome Inventory-14 (TOI-14), is now available to measure quality of life in adults with chronic tonsillitis (CTO). This validated tool aids in assessing health-related quality of life (HR-QOL) and treatment outcomes.
Area of Science:
- Otolaryngology
- Health Services Research
- Quality of Life Research
Background:
- No validated instrument existed to measure disease-specific health-related quality of life (HR-QOL) in adults with chronic tonsillitis (CTO).
- Chronic tonsillitis significantly impacts patients' quality of life, necessitating a reliable assessment tool.
Purpose of the Study:
- To develop and validate the Tonsillectomy Outcome Inventory-14 (TOI-14) as a disease-specific instrument for measuring HR-QOL in adults with CTO.
- To assess the reliability, validity, and sensitivity of the TOI-14.
Main Methods:
- An alpha-version of the Tonsillectomy Outcome Inventory (TOI) underwent item reduction to create the TOI-14.
- The TOI-14, including total score and subscales (throat problems, overall health, resources, social-psychological restrictions), was prospectively validated in 108 adults with CTO post-tonsillectomy.
Main Results:
- The TOI-14 demonstrated good reliability and included key aspects of HR-QOL.
- The questionnaire showed high sensitivity in distinguishing patients with CTO from healthy individuals.
- Scores correlated moderately to highly with subjective quality of life limitations, with significant postoperative effects observed.
Conclusions:
- The TOI-14 is the first globally validated, disease-specific instrument for assessing HR-QOL in adults with CTO.
- Its ease of use makes it suitable for both outcome research and clinical practice.
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