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Updated: Aug 16, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
IgG4 antibodies in hay fever patients. Difference in IgG4 response to tree pollen and grass pollen allergens
E V Chernokhvostova1, T S Kotova, G P German
1Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, USSR.
Abstract:
Total IgE and IgE and IgG4 antibodies to offending allergens were studied in 118 hay fever patients allergic to tree pollen and grass pollen allergens. No difference in the level of total IgE and IgE antibodies was found between these two groups while the IgG4 antibody level was significantly higher in tree pollen allergic patients. It is suggested that the IgG4 antibodies to tree pollen allergens can be stimulated by structurally related allergens of vegetable food and are probably involved in tree pollen-associated food hypersensitivity.
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