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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Formal synthesis of merrilactone A using a domino cyanide 1,4-addition-aldol cyclization

Naim Nazef1, Robert D M Davies, Michael F Greaney

  • 1School of Chemistry, University of Manchester , Oxford Road, Manchester M13 9PL, U.K., School of Chemistry, University of Edinburgh , Joseph Black Building, King's Buildings, West Mains Road, Edinburgh EH9 3JJ, U.K., and AstraZeneca , Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, U.K.

Organic Letters
|July 10, 2012
PubMed

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