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Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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Live imaging using adaptive optics with fluorescent protein guide-stars.

Xiaodong Tao1, Justin Crest, Shaila Kotadia

  • 1W.M. Keck Center for Adaptive Optical Microscopy, Jack Baskin School of Engineering, University of California, Santa Cruz, California 95064, USA. taoxd@soe.ucsc.edu

Optics Express
|July 10, 2012
PubMed
Summary

We developed an adaptive optical microscope using fluorescent guide-stars to correct aberrations in live imaging. This technique achieves near diffraction-limited resolution for dynamic imaging of biological samples like Drosophila embryos.

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