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Traumatic stress in Lymnaea snails causes a prolonged heightened shadow withdrawal response (SWR) and suppressed other behaviors. This is linked to significant electrophysiological changes in the RPeD11 interneuron, increasing defensive alert levels.

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Area of Science:

  • Neuroscience
  • Behavioral Biology
  • Stress Research

Background:

  • Stress significantly impacts adaptive behaviors, including vigilance.
  • In Lymnaea, the shadow withdrawal response (SWR) is a key vigilance behavior mediated by dermal photoreceptors.
  • The neural mechanisms underlying stress-induced behavioral changes require further investigation.

Purpose of the Study:

  • To identify neural correlates of heightened SWR and other behaviors following traumatic stress in Lymnaea.
  • To investigate electrophysiological changes in the RPeD11 interneuron after trauma.
  • To determine the duration of stress-induced behavioral and neuronal alterations.

Main Methods:

  • Electrophysiological properties of the RPeD11 interneuron were measured in traumatized and naive Lymnaea snails.
  • Behavioral responses to shadow stimuli were assessed 24 hours and one week post-trauma.
  • Locomotive, feeding, and respiratory behaviors were also monitored.

Main Results:

  • Traumatized snails exhibited an augmented SWR and suppressed locomotive, feeding, and respiratory behaviors for at least one week.
  • The RPeD11 interneuron in traumatized snails showed significant depolarization (∼10 mV) and increased input resistance.
  • The duration of the RPeD11 response to shadow stimuli was prolonged in traumatized preparations.

Conclusions:

  • Traumatic stress induces lasting behavioral and neuronal changes in Lymnaea, characterized by heightened SWR and altered RPeD11 function.
  • The observed changes in RPeD11 contribute to an elevated defensive alert state in stressed snails.
  • This study provides a neural basis for understanding stress-induced vigilance and behavioral suppression.