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Related Concept Videos

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 20, 2026

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
07:31

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

Published on: May 24, 2016

Breast metastasis from a melanoma.

Ahmad Al Samaraee1, Hazem Khout, Tarig Barakat

  • 1Department of General Surgery, Queen Elizabeth Hospital, Gateshead, UK.

Ochsner Journal
|July 11, 2012
PubMed
Summary

Metastatic melanoma, though rare, can present as a secondary breast tumor in women with a history of cancer. This case highlights the importance of considering metastatic disease in breast lumps.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Breast tumors are common, with benign and primary malignant types being most frequent.
  • Secondary tumors in the breast, originating from distant cancers, are uncommon but clinically significant.

Observation:

  • A premenopausal woman presented with a breast lump.
  • She had a history of a primary malignant tumor.

Findings:

  • The breast lump was diagnosed as a metastatic melanoma.
  • This represents a rare instance of secondary breast malignancy.

Implications:

  • Metastasis to the breast should be considered in patients with a known history of malignancy presenting with breast masses.
  • This underscores the need for thorough diagnostic evaluation in such cases.
Keywords:
Breast malignanciesbreast metastasesmelanoma

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