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[Urolithiasis risk factors in obese and overweight children]

Hanna Borysewicz-Sańczyk1, Tadeusz Porowski, Andrzej Hryniewicz

  • 1Klinika Pediatrii, Endokrynologii, Diabetologii, Uniwersytetu Medycznego w Bialymstoku, Bialystok. hannaborysewicz@poczta.fm

Pediatric Endocrinology, Diabetes, and Metabolism
|July 12, 2012
PubMed

Insights

Childhood obesity is linked to higher risks of kidney stones. Overweight children show increased urine oxalate and lower citrate levels, indicating a greater propensity for stone formation.

Area of Science:

  • Pediatric Nephrology
  • Metabolic Disorders
  • Urology

Context:

  • Childhood obesity is a growing global health concern with potential long-term complications.
  • Obesity is a known risk factor for kidney disease and urolithiasis in adults.
  • Early identification of risk factors in children is crucial for preventative strategies.

Purpose:

  • To investigate the association between overweight/obesity and risk factors for urolithiasis in children.
  • To compare urinary stone risk parameters between obese/overweight children and normal-weight controls.

Summary:

  • Analyzed urinary calcium, oxalate, citrate, and pH in 249 overweight/obese children and 281 normal-weight children (ages 3-18).
  • Found significantly higher mean urine oxalate and lower mean urine citrate concentrations in overweight/obese children.
  • Observed significantly lower mean urine pH in overweight/obese children compared to controls.

Impact:

  • Findings suggest that overweight and obesity in children are associated with an elevated risk of kidney stone formation.
  • Highlights the potential role of weight management in preventing pediatric urolithiasis.
  • Provides evidence for early intervention in pediatric obesity to mitigate renal health risks.
Abstract

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