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Published on: May 10, 2024
Wheezing in infants: frequency, clinical characteristics and treatment
Maiara Lanna Bouzas1, Dirceu Solé, Maria Regina A Cardoso
1Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil. maiara.lanna@gmail.com
Insights
One-third of infants aged 6-23 months reported prior wheezing, with earlier onset linked to more frequent recurrence. This highlights early wheezing as a key indicator in infant respiratory health.
Area of Science:
- Pediatrics
- Respiratory Medicine
- Epidemiology
Background:
- Wheezing in infants is a common respiratory symptom.
- Understanding the frequency and characteristics of early wheezing is crucial for diagnosis and management.
- Previous history of wheezing can indicate underlying respiratory vulnerabilities.
Purpose of the Study:
- To determine the prevalence of prior wheezing history in infants.
- To describe the clinical features and treatments associated with infant wheezing.
- To identify factors influencing wheezing recurrence in young children.
Main Methods:
- Retrospective follow-up of 451 infants aged 6-23 months presenting with upper respiratory tract complaints.
- Inclusion criteria required a reported history of previous wheezing.
- Data collected using a validated standardized form.
Main Results:
- A history of wheezing was reported by 36.4% of infants, with 32.8% experiencing it in their first year of life.
- The mean age of the first wheezing episode was 5.3 months.
- Infants with their first episode before 12 months had higher recurrence rates (38.5% with 3-6 episodes, 14.2% with >6 episodes).
Conclusions:
- Approximately one-third of infants experience wheezing within their first year.
- Earlier onset of the first wheezing episode is significantly associated with more frequent recurrences.
- Early wheezing episodes in infancy may predict a more persistent or severe course.
Objective:
To estimate the frequency and describe the clinical characteristics and respective treatments of previous history of wheezing.
Methods:
Infants aged 6-23 months with upper respiratory tract complaints and reporting previous wheezing were followed-up retrospectively. Data were registered on a validated standardized form.
Results:
Out of 451 infants, 164 (36.4%; 95%CI:31.9-41.0) had a report of prior history of wheezing, 148 (32.8%; 95%CI:28.5-37.4) during the first year of life. The mean age at the first episode of wheezing was 5.3±3.9 months. Among those who had had their first episode before 12 months of age, 38.5% reported 3 to 6 episodes and 14.2% > 6 episodes. Mean age at first episode was lower for those with ≥ 3 episodes in comparison with those with ≤ 2 episodes (3.2±2.7 vs. 5.7±2.5 months, p < 0.001).
Conclusion:
One third of the infants reported wheezing during the first year of life. The earlier the first episode occurs, the more frequently wheezing recurs.
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