Palladium(0)-catalyzed dearomative arylation of indoles: convenient access to spiroindolenine derivatives
Ke-Jia Wu1, Li-Xin Dai, Shu-Li You
1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
Abstract:
Dearomatization of an indole via palladium(0)-catalyzed cross-coupling reaction has been realized. With readily available triphenylphosphine as ligand, various spiroindolenine derivatives have been obtained in good to excellent yields, and enantioselective control is also feasible with chiral ligands.
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