Related Experiment Video
Updated: May 20, 2026

14:22
Activating Molecules, Ions, and Solid Particles with Acoustic Cavitation
Published on: April 11, 2014
Ultrasonic activation of internal bleaching agents
M Cardoso1, C S M Martinelli, C A T Carvalho
1Dental Materials and Prosthodontics Department, São José dos Campos Dental School, Unesp, Univ Estadual Paulista, São José dos Campos, SP, Brazil. mayra.cardoso@bol.com.br
International Endodontic Journal
|July 14, 2012
Summary
Ultrasonic activation of bleaching agents for internal tooth bleaching showed no significant improvement over conventional methods. This study found no added benefit of using ultrasound with sodium perborate, carbamide peroxide, or hydrogen peroxide gels.
Area of Science:
- Endodontics
- Restorative Dentistry
- Dental Materials Science
Background:
- Internal bleaching is a common procedure for discolored teeth.
- Conventional internal bleaching involves placing bleaching agents within the pulp chamber.
- The use of ultrasonic activation aims to enhance the efficacy of bleaching agents.
Purpose of the Study:
- To investigate the effectiveness of ultrasonic activation of bleaching agents for ex vivo internal bleaching.
- To compare ultrasonic activation with conventional internal bleaching techniques.
Main Methods:
- Fifty human canine teeth were artificially stained and root-filled.
- Teeth were divided into five groups: sodium perborate (SP), carbamide peroxide (CP), CP with ultrasonic activation (CPUS), hydrogen peroxide (HP), and HP with ultrasonic activation (HPUS).
- Color change was measured using a dental spectrophotometer after two bleaching sessions, analyzing CIELab parameters (L*, a*, b*, ΔE*).
Main Results:
- No significant differences were found in ΔL*, Δa*, or ΔE* among the groups.
- A significant difference was observed in Δb* after both sessions.
- While HP and HPUS showed greater Δb* after the first session, HPUS demonstrated the highest Δb* after the second session, though similar to HP and SP.
Conclusions:
- Ultrasonic activation of bleaching agents does not enhance the effectiveness of ex vivo internal bleaching compared to conventional methods.
- The study suggests that conventional internal bleaching procedures are as effective as those with ultrasonic activation.

