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Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
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T regulatory cell therapy in transplantation: stability, localization and functional specialization

Katherine G MacDonald1, Paul C Orban, Megan K Levings

  • 1Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.

Current Opinion in Organ Transplantation
|July 14, 2012
PubMed
Summary

Regulatory T cells (Tregs) hold promise for transplantation tolerance by reducing immunosuppression. Optimizing Treg function and survival post-transfer is crucial for successful cellular therapy in vivo.

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