Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

496
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
496
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

405
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
405
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

440
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
440
The ABO Blood Group01:12

The ABO Blood Group

5.2K
The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
5.2K
Kidney Structure01:45

Kidney Structure

75.5K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.5K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

3.9K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IL-16 production is a mechanism of resistance to BTK inhibitors and R-CHOP in lymphomas.

Blood·2026
Same author

Flow Cytometry-Based Measurable Residual Disease Assessment in Patients With Acute Myeloid Leukemia Receiving Non-Intensive Chemotherapy.

American journal of hematology·2026
Same author

Polatuzumab vedotin and CD79B: A study of efficacy in R-CHOP-resistant diffuse large B-cell lymphoma.

British journal of haematology·2025
Same author

Respiratory Syncytial Virus Vaccination in Adult Allogeneic Hematopoietic Cell Transplant Recipients.

JAMA·2025
Same author

Updated recommendations for the treatment of light-chain amyloidosis from the Swiss Amyloidosis Network.

Swiss medical weekly·2025
Same author

IL-16 production is a mechanism of resistance to BTK inhibitors and R-CHOP in lymphomas.

bioRxiv : the preprint server for biology·2025
Same journal

Introduction to pediatric solid organ transplantation - not just little adults!

Current opinion in organ transplantation·2026
Same journal

Editorial introduction.

Current opinion in organ transplantation·2026
Same journal

Precision medicine guided development of new immunosuppression strategies in solid organ transplantation.

Current opinion in organ transplantation·2026
Same journal

Intestinal transplantation for tumors.

Current opinion in organ transplantation·2026
Same journal

Current state of medical rehabilitation for adult short bowel syndrome patients with intestinal failure.

Current opinion in organ transplantation·2026
Same journal

Update on costimulatory blockade in transplantation: a review of recent literature.

Current opinion in organ transplantation·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

139

ABO-incompatible kidney transplantation.

Thomas Fehr1, Georg Stussi

  • 1Division of Nephrology, Zurich Transplant Center and University Hospital, Zurich, Switzerland. thomas.fehr@uzh.ch

Current Opinion in Organ Transplantation
|July 14, 2012
PubMed
Summary
This summary is machine-generated.

ABO-incompatible kidney transplantation offers comparable patient and graft survival to ABO-compatible procedures. This approach expands the donor pool, with B-cell depletion and careful steroid management improving outcomes.

More Related Videos

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K
Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

17.3K

Related Experiment Videos

Last Updated: Feb 11, 2026

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

139
Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K
Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

17.3K

Area of Science:

  • Nephrology
  • Transplantation Immunology
  • Organ Transplantation

Background:

  • Global organ shortage necessitates innovative transplantation strategies.
  • Overcoming immunological barriers is crucial for expanding kidney transplant options.

Purpose of the Study:

  • To review recent outcomes of ABO-incompatible kidney transplantation.
  • To assess the efficacy and safety of current protocols.

Main Methods:

  • Review of recent clinical results and long-term follow-up studies.
  • Analysis of patient and graft survival rates.
  • Evaluation of immunosuppressive protocols including B-cell depletion and corticosteroids.

Main Results:

  • Patient and graft survival in ABO-incompatible kidney transplants are comparable to ABO-compatible transplants.
  • Rituximab has replaced splenectomy, improving graft survival but potentially increasing infection risk.
  • Long-term accommodation involves complement inhibitor upregulation and endothelial chimerism.

Conclusions:

  • ABO-incompatible kidney transplantation is effective and well-tolerated in adults and children.
  • This method significantly expands the living donor pool.
  • Understanding graft accommodation may benefit recipients with human leukocyte antigen sensitization.