Related Experiment Video
Updated: May 20, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
An atypical pneumococcal arthritis
Pascal Rossi1, Brigitte Granel, Philippe Mouly
1Department of Internal Medicine, Hopital Nord, Marseille, France. pascalmaurice.rossi@ap-hm.fr
Abstract:
Bone and joint infections due to Streptococcus pneumoniae usually occur in patients who are immunocompromised, and involve one site. The unique case of a 49-year-old immunocompetent man, with an unremarkable medical history, with septicaemia and polyarticular septic arthritis involving the shoulder and knee and with cervical spondylodiscitis due to S pneumoniae, is described. In this case, S pneumoniae probably originated from the gingiva, which is commonly colonised in children and adults. S pneumoniae should be considered routinely when facing bone and joint infections, and multiple locations should be carefully sought owing to the possible lack of symptoms.
Insights
Streptococcus pneumoniae can cause bone and joint infections, even in healthy individuals. This case highlights the importance of checking multiple sites for infection, as it may spread from the mouth.
Area of Science:
- Infectious Diseases
- Rheumatology
- Microbiology
Background:
- Bone and joint infections are typically seen in immunocompromised patients and affect a single site.
- Streptococcus pneumoniae is a common pathogen, but severe disseminated infections are less frequent in immunocompetent individuals.
Observation:
- A 49-year-old immunocompetent male presented with sepsis and polyarticular septic arthritis affecting the shoulder and knee.
- The patient also had cervical spondylodiscitis, a rare spinal infection, caused by Streptococcus pneumoniae.
Findings:
- This case represents a unique presentation of Streptococcus pneumoniae causing simultaneous, multiple-site bone and joint infections in an immunocompetent host.
- The likely origin of the infection was the gingiva, a common colonization site for S. pneumoniae.
Implications:
- Streptococcus pneumoniae should be routinely considered in the differential diagnosis of bone and joint infections, regardless of immune status.
- Clinicians should actively investigate for multiple infected sites, even in the absence of overt symptoms, to ensure comprehensive diagnosis and treatment.
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia II: Pathophysiology
Pneumonia III: Complications and Assessment
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause: