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Updated: May 20, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic gastrointestinal diseases: review and update
Mahreema Jawairia1, Ghulamullah Shahzad, Paul Mustacchia
1Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
ISRN Gastroenterology
|July 14, 2012
Summary
Eosinophilic gastrointestinal disorders (EGIDs) are increasingly common. This review highlights recent advancements in EGID patient care and the complex role of eosinophils in gastrointestinal health.
Area of Science:
- Gastroenterology
- Immunology
Background:
- Eosinophilic gastrointestinal disorders (EGIDs) represent a growing spectrum of intestinal diseases.
- These conditions involve eosinophil accumulation and activation within the gastrointestinal tract.
Purpose of the Study:
- To present the latest developments in managing patients with EGIDs.
- To synthesize current literature on EGID clinical features and the mechanisms of eosinophil involvement in the GI tract.
Main Methods:
- Comprehensive literature review of recent studies on EGIDs.
- Analysis of clinical presentations and mechanistic insights into eosinophil-Gastrointestinal tract interactions.
Main Results:
- EGIDs are increasingly recognized, necessitating heightened clinical awareness.
- Eosinophil activity is intricately linked to gastrointestinal dysfunction in these disorders.
Conclusions:
- Clinicians should consider EGIDs in patients presenting with non-specific gastrointestinal symptoms.
- Further research is crucial to understand the pathways leading to eosinophilic gastrointestinal inflammation and dysfunction.
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