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Updated: May 20, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Defining patient-reported outcomes in chronic obstructive pulmonary disease: the patient-centered experience
Jonathan P Singer1, Roger D Yusen
1Division of Pulmonary, Critical Care, Allergy and Sleep Medicine and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94117, USA. jon.singer@ucsf.edu
Abstract:
Patients with COPD have reduced HRQOL, and HRQOL worsens as COPD progresses.Although long-term interventions such as smoking cessation, supplemental oxygen therapy for hypoxemia, LVRS, and lung transplantation may save lives, these and other therapies have variable but important effects on PROs. Measures of HRQOL can serve as measures of disease severity and predict outcome. Moreover, these measures are sensitive to change following interventions, and can thus be used as measures of intervention effect. Future research will provide a better understanding of the effects of COPD on HRQOL and the impact of various interventions.
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