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Treating constrictive pericarditis in a chinese single-center study: a five-year experience

Yiyun Lin1, Mi Zhou, Jian Xiao

  • 1Department of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.

The Annals of Thoracic Surgery
|July 17, 2012
PubMed

Insights

Prompt surgical treatment for constrictive pericarditis is crucial. Early pericardiectomy and post-operative care significantly improve survival rates, though factors like elevated erythrocyte sedimentation rate indicate higher mortality risk.

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Infectious Disease

Background:

  • Constrictive pericarditis is a rare but serious condition causing pericardial thickening.
  • Prompt diagnosis and intervention are vital to reduce patient morbidity and mortality.

Purpose of the Study:

  • To analyze surgical outcomes for patients with constrictive pericarditis.
  • To identify factors influencing mortality and survival post-pericardiectomy.

Main Methods:

  • Retrospective analysis of 51 constrictive pericarditis patients undergoing surgery (Jan 2005-Dec 2010).
  • Surgical intervention involved total pericardiectomy via midline sternotomy.

Main Results:

  • Tuberculous pericarditis was the most common cause (65%).
  • In-hospital mortality was 3.9%, with causes including low cardiac output syndrome and renal failure.
  • One-year survival was 93.7%; elevated erythrocyte sedimentation rate, abnormal creatinine, low output syndrome, and pleural effusion were linked to increased mortality.

Conclusions:

  • Early diagnosis and pericardiectomy are essential for managing constrictive pericarditis.
  • Post-operative management including inotropes, diuretics, and salt restriction is critical for prognosis.
  • Monitoring erythrocyte sedimentation rate during follow-up is recommended to assess inflammation and risk.
Abstract

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