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Published on: February 11, 2022
Treating constrictive pericarditis in a chinese single-center study: a five-year experience.
Yiyun Lin1, Mi Zhou, Jian Xiao
1Department of Cardiothoracic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
The Annals of Thoracic Surgery
|July 17, 2012
Summary
Prompt surgical treatment for constrictive pericarditis is crucial. Early pericardiectomy and post-operative care significantly improve survival rates, though factors like elevated erythrocyte sedimentation rate indicate higher mortality risk.
Area of Science:
- Cardiology
- Thoracic Surgery
- Infectious Disease
Background:
- Constrictive pericarditis is a rare but serious condition causing pericardial thickening.
- Prompt diagnosis and intervention are vital to reduce patient morbidity and mortality.
Purpose of the Study:
- To analyze surgical outcomes for patients with constrictive pericarditis.
- To identify factors influencing mortality and survival post-pericardiectomy.
Main Methods:
- Retrospective analysis of 51 constrictive pericarditis patients undergoing surgery (Jan 2005-Dec 2010).
- Surgical intervention involved total pericardiectomy via midline sternotomy.
Main Results:
- Tuberculous pericarditis was the most common cause (65%).
- In-hospital mortality was 3.9%, with causes including low cardiac output syndrome and renal failure.
- One-year survival was 93.7%; elevated erythrocyte sedimentation rate, abnormal creatinine, low output syndrome, and pleural effusion were linked to increased mortality.
Conclusions:
- Early diagnosis and pericardiectomy are essential for managing constrictive pericarditis.
- Post-operative management including inotropes, diuretics, and salt restriction is critical for prognosis.
- Monitoring erythrocyte sedimentation rate during follow-up is recommended to assess inflammation and risk.
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