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Updated: May 20, 2026
06:46
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
3-[(E)-(Pyridin-3-yl-imino)-meth-yl]phenol
Summary
This study details the crystal structure of a compound containing 3-hydroxybenzaldehyde and pyridin-3-amine units. The molecules form dimers through hydrogen bonds and exhibit pi-pi interactions between aromatic rings.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding molecular interactions is crucial in crystal engineering.
- The title compound, C(12)H(10)N(2)O, combines 3-hydroxybenzaldehyde and pyridin-3-amine moieties.
- Crystal structure analysis reveals the spatial arrangement and intermolecular forces.
Purpose of the Study:
- To elucidate the crystal structure of the title compound.
- To investigate the intermolecular interactions, including hydrogen bonding and pi-pi stacking.
- To characterize the molecular geometry and symmetry in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles provided geometric insights.
- Intermolecular interactions were identified and quantified using hydrogen bond analysis and pi-pi interaction calculations.
Main Results:
- Two independent molecules were found in the asymmetric unit, with near-planar 3-hydroxybenzaldehyde and pyridin-3-amine units.
- Molecules form inversion dimers via O-H⋯N hydrogen bonds, creating R(2)(2)(20) ring motifs.
- Significant pi-pi interactions were observed between benzene and pyridine rings with specific centroid-centroid distances.
Conclusions:
- The crystal structure is stabilized by a combination of hydrogen bonding and pi-pi interactions.
- The observed supramolecular architecture provides insights into crystal packing and molecular assembly.
- The study contributes to the understanding of structure-property relationships in organic crystalline materials.
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