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Updated: May 20, 2026
12:37
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Radiation therapy for cutaneous melanoma.
Christopher A Barker1, Nancy Y Lee
1Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. barkerc@mskcc.org
Dermatologic Clinics
|July 18, 2012
Summary
Radiation therapy offers high control rates for primary cutaneous melanoma and improves regional control when used adjuvantly. This evidence supports its integration into optimal melanoma patient care.
Area of Science:
- Oncology
- Dermatology
- Radiation Oncology
Background:
- Cutaneous melanoma treatment infrequently utilizes radiation therapy.
- Emerging research indicates potential benefits in specific clinical situations.
Purpose of the Study:
- To review the highest level of evidence supporting radiation therapy for cutaneous melanoma.
- To highlight the role of radiation therapy in managing melanoma.
Main Methods:
- Review of retrospective and prospective studies.
- Analysis of two randomized trials on adjuvant radiotherapy.
Main Results:
- Radiation therapy for primary tumors shows high control rates.
- Adjuvant radiotherapy to regional lymphatics improves regional control.
- Radiation therapy demonstrates palliative response and metastatic tumor control.
Conclusions:
- Radiation therapy is a valuable component of optimal cutaneous melanoma care.
- Clinicians should be aware of the evidence supporting radiation therapy in melanoma management.
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