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A child with pulmonary and liver Langerhans'-cell histiocytosis
Xiao-Li Ma1, Kun-Ling Shen, Bin Wang
1Hematology Center, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
Abstract:
Clinical categories of Langerhans cell histiocytosis (LCH) include single and multi-system disease. Pulmonary LCH is rare, which is an unusual interstitial lung disease with the characteristics of monoclonal proliferation and infiltration of Langerhans' cells to organs. We report our experience of a rare LCH case of multiple organs such as pulmonary and liver as the main clinical manifestation. The patient was treated with chemotherapy which included prednisone, vinblastine, methotrexate and 6-mercaptopurine for 52 weeks and follow up all along. The patient has a favorable clinical outcome.
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