Related Experiment Video
Updated: May 20, 2026

Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm
Published on: June 7, 2018
[Evolution of the need and coverage of opioid substitution treatments and needle exchange programmes in Spanish
L de la Fuente1, M J Bravo, E Jiménez-Mejías
1Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, España.
Introduction:
Spain is one of the few countries to have widely implemented opioid substitution treatments (OST) and needle exchange programmes (NEP) for drug users in prison. We analyze the evolution of the need, coverage and the timeliness of these interventions in Spain between 1992 and 2009.
Methods:
Data on the provision of interventions is taken from official publications. The need was calculated by applying multiplicative methods to secondary data from several sources. Coverage was estimated as the quotient between provision and need. Temporal opportunity was estimated by observing the gap between the acme of the incidence of consumption, of HIV infection or need and the curve of provision.
Results:
OST's began to be implemented in 1992. In 2002 they reached their maximum coverage (63.8%) and subsequently stabilized. NEP's started in 1997. Their maximum coverage reached 20.7% in 2006, but halved in a period of two years. The delay between the epidemic acme and the need and maximum intervention coverage was of 8-25 years.
Conclusions:
OST and NEP introduction in Spanish prisons was a great advance, but the delay in their implementation and the low level of NEP coverage could have limited their potential impact on the improvement of the health of incarcerated drug users. The decline of NEP coverage in recent years is a cause of major concern for the evolution of HIV and Hepatitis C epidemics.
More Related Videos
Related Concept Videos
Drug Dependence
Drug Abuse and Addiction: Pharmacological Phenomena
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Drug Control Governance: Regulatory Bodies and Their Impact
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

