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Antidepressants and bleeding risk after face-lift surgery.

Sanaz Harirchian¹, Richard A Zoumalan, David B Rosenberg

¹Department of Otolaryngology–Head and Neck Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA. harirs02@gmail.com

Archives of Facial Plastic Surgery

|July 18, 2012

Summary

Selective serotonin reuptake inhibitors (SSRIs) did not increase the risk of hematoma after face-lift surgery. Continuing SSRIs perioperatively is safe and does not appear to negatively impact outcomes in these patients.

Related Experiment Videos

Area of Science:

Plastic Surgery
Pharmacology

Background:

Selective serotonin reuptake inhibitors (SSRIs) are commonly used antidepressants.
Concerns exist regarding potential bleeding risks associated with SSRIs.
Discontinuing SSRIs perioperatively carries its own set of risks.

Purpose of the Study:

To compare the incidence of post-face-lift hematoma in patients using SSRIs versus those not using SSRIs.
To evaluate the safety of perioperative SSRI use in patients undergoing face-lift procedures.

Main Methods:

Retrospective review of medical charts for 263 patients undergoing face-lift or neck-lift surgery.
Analysis of postoperative hematoma incidence based on SSRI/SNRI usage.
Examination of patient comorbidities and medication lists.

Main Results:

Twenty-two percent of patients were taking SSRIs or serotonin-norepinephrine reuptake inhibitors (SNRIs).
Overall hematoma rate was 1.95% for non-SSRI/SNRI users and 1.72% for SSRI/SNRI users.
Minor hematoma rate was 1.95% in non-users vs. 0% in users; major hematoma rate was 0% in non-users vs. 1.72% in users.

Conclusions:

SSRI usage was prevalent in this cohort of face-lift patients.
Perioperative SSRI use was found to be safe in this study population.
No evidence supports discontinuing SSRIs before face-lift surgery.