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Assisted reproductive technology treatment outcomes.

M Naasan1, J Waterstone, M M Johnston

  • 1Human Assisted Reproduction Ireland, Rotunda Hospital, Parnell St, Dublin 1. mashhournaasan@yahoo.co.uk

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Irish fertility treatment outcomes are presented from a 10-year analysis of voluntary reports from six IVF clinics. The study confirms assisted reproductive technology (ART) practice in Ireland is safe and effective.

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Area of Science:

  • Reproductive Medicine
  • Clinical Embryology
  • Public Health Policy

Background:

  • Limited availability of assisted reproductive technology (ART) treatment outcomes data for Irish practitioners.
  • Hospital-affiliated clinics have historically reported ART data, but comprehensive national data has been lacking.
  • Voluntary reporting by fertility clinics is crucial for understanding national ART trends.

Purpose of the Study:

  • To present a comprehensive 10-year analysis of ART treatment outcomes in Ireland.
  • To evaluate the safety, effectiveness, and responsible practice of ART in the Irish context.
  • To inform potential policy changes, such as state funding for IVF and single embryo transfer.

Main Methods:

  • Analysis of voluntarily reported data from six out of seven Irish IVF clinics over a 10-year period.
  • Inclusion of data from published European Society of Human Reproduction and Embryology (ESHRE) reports and unpublished 2007-2008 results.
  • Collection of data on clinic numbers, ART cycles, female age, pregnancy rates (clinical and multiple), and treatment complications.

Main Results:

  • Clinical pregnancy rates per embryo transfer were 31.7% for In Vitro Fertilization (IVF) and 29.8% for Intracytoplasmic Sperm Injection (ICSI).
  • Delivery proportions for IVF and ICSI combined were 75% singleton, 23.35% twin, and 1.64% triplet.
  • The rate of ovarian hyperstimulation syndrome was 0.8%, indicating a safe treatment profile.

Conclusions:

  • ART practice in Ireland is demonstrated to be safe, effective, and responsible.
  • Potential financial and societal savings could be achieved through state-funded IVF programs.
  • Compulsory elective single embryo transfer (eSET) where clinically recommended could optimize resource utilization and patient outcomes.