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Updated: May 20, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Effect of hospital admission on glycemic control 1 year after discharge
Nancy J Wei1, Richard W Grant, David M Nathan
1Diabetes Center, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA. ncwei@partners.org
Insights
Hospital admission did not significantly alter long-term glycemic control trends in diabetes patients. However, hospitalized individuals were less likely to reach target hemoglobin A1c levels one year post-discharge.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Clinical Medicine
Background:
- Diabetes mellitus management requires continuous monitoring of glycemic control.
- Hospitalization can disrupt routine diabetes care and impact long-term health outcomes.
- Assessing the effect of inpatient stays on diabetes control is crucial for patient management.
Purpose of the Study:
- To evaluate the impact of hospital admission on glycemic control in patients with diabetes.
- To compare glycemic control trajectories up to one year after discharge between hospitalized and non-hospitalized individuals.
- To identify factors influencing the achievement of glycemic targets post-hospitalization.
Main Methods:
- Retrospective analysis of 826 hospitalized and 826 matched non-hospitalized adults with diabetes.
- Collected hemoglobin A1c (A1C) data from 6 months pre-admission to 1 year post-discharge.
- Utilized multivariate random effects models and logistic regression for data analysis.
Main Results:
- No significant difference in the mean rate of A1C change between hospitalized and non-hospitalized patients over one year.
- Hospitalized patients were less likely to achieve A1C goals of ≤7% (OR, 0.68) or <8% (OR, 0.62) at one year.
- Patients with baseline A1C ≥9% showed a trend of -0.10% monthly A1C change, irrespective of hospitalization.
Conclusions:
- Hospitalization does not alter the overall trend of glycemic improvement over time.
- Hospitalized patients with uncontrolled diabetes face greater challenges in achieving long-term glycemic targets.
- There is a potential missed opportunity to optimize long-term diabetes management during hospital admissions.
Objective:
To assess the effect of hospital admission on glycemic control in patients with diabetes up to 1 year after discharge.
Methods:
We retrospectively studied 826 adults with diabetes admitted to a tertiary care medical center and with available hemoglobin A1c (A1C) values for 6 months before admission and 1 year after discharge. We compared them with 826 nonhospitalized adults with diabetes matched for age, sex, race, comorbidity, and baseline A1C level. We determined the change in A1C value relative to hospitalization and baseline A1C level by using multivariate random effects models for repeated measures. Logistic regression analysis was performed to determine predictors of achieving recommended A1C levels at 1 year.
Results:
Patients with baseline A1C levels ≥9% had an adjusted rate of change in A1C value of -0.10% per month (95% confidence interval [CI], -0.18 to -0.022; P=.012) during the course of 1 year, without significant differences between hospitalized and nonhospitalized patients in the mean rate of change. Hospitalized patients, however, were less likely to achieve an A1C goal of ≤7% at 1 year (odds ratio, 0.68; 95% CI, 0.55 to 0.86; P<.001) or an A1C of <8% at 1 year (odds ratio, 0.62; 95% CI, 0.48 to 0.81; P<.001) in comparison with the nonhospitalized patients.
Conclusion:
Despite an overall trend toward improved glycemia over time, hospitalized patients with uncontrolled diabetes were less likely to achieve glycemic targets at 1 year in comparison with matched nonhospitalized patients. These results suggest a missed opportunity to improve long-term glycemic control in hospitalized patients with diabetes.
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