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Updated: May 20, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Feasibility study for the improvement of microcalcification visualization in different breast thicknesses and tissue
Chia-Jung Tsai1, Ran-Chou Chen, Shuo-Hui Hung
1Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan.
Objective:
The purpose of this study was to improve detectability of microcalcifications using a dual-energy digital mammographic (DEDM) technique.
Methods:
Slabs of uniform breast-equivalent plastic and an additional plate were used to mimic various breast thicknesses, from 3 to 7 cm, and to simulate microcalcification with diameters from 0.16 to 0.39 mm. Free-response receiver operating characteristics and area under the curves (Az) were used to evaluate the sensitivity of detecting microcalcifications using the DEDM compared with using the conventional single-energy digital mammography (SEDM).
Results:
The mean number of false-positives per image was 0.0198 (Az = 0.956 ± 0.027) using DEDM compared with 0.292 (Az = 0.681 ± 0.235) using SEDM. A lower radiation dose could be possibly obtained for the DEDM technique with a thickness of less than 5 cm compared with the SEDM with a thickness larger than 5 cm.
Conclusions:
Microcalcifications could be more accurately and efficiently detected using the DEDM, which might bring reliable and promising applications on early computer-aided diagnosis of breast cancer.
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