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Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Giant sacral schwannomas
Sedat Çağlı1, Hasan Serdar Işık, Umut Yıldırım
1Department of Neurosurgery, Ege University Faculty of Medicine, Izmir, Turkey.
Journal of Neuro-Oncology
|July 19, 2012
Summary
Sacral schwannomas, rare tumors, can be diagnosed using CT and MRI. Biopsy is recommended before surgery for appropriate treatment, with intralesionary excision being an effective surgical choice.
Area of Science:
- Neurosurgery
- Oncology
- Radiology
Background:
- Sacral schwannomas are exceptionally rare tumors, with limited case series reported.
- Diagnosis often relies on imaging, but pre-operative biopsy aids treatment planning.
Purpose of the Study:
- To present an extensive case series of sacral schwannomas.
- To evaluate diagnostic modalities and surgical outcomes for these rare tumors.
Main Methods:
- Retrospective analysis of 13 patients with giant sacral schwannomas operated between 1995 and 2010.
- Diagnosis confirmed via radiography, CT, MRI, and biopsy (Sridhar Type V classification).
- Surgical approaches included anterior, posterior, or combined interventions with intralesionary resection.
Main Results:
- All patients presented with back and leg pain; some experienced sphincter issues or leg weakness.
- Intralesionary resection was performed, with anterior/posterior or combined approaches utilized.
- One patient experienced iliac vein injury requiring reoperation; residual tumors in two patients did not necessitate further surgery.
Conclusions:
- CT and MRI are effective for diagnosing sacral schwannomas.
- Pre-operative biopsy is crucial for determining treatment strategy.
- Simple intralesionary excision is a suitable surgical option for sacral schwannomas.
