Concomitant choroidal melanoma and non-hodgkin lymphoma in two adult patients: case report
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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Marcel Vlaskamp1, Didi de Wolff-Rouendaal, Patty M Jansen
1Department of Ophthalmology, LUMC, Leiden, The Netherlands.
Objective:
To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients.
Design:
Case report.
Participants:
Two patients with yellow creamy infiltrates in fundo.
Intervention:
Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye.
Main Outcome Measures:
Histology findings of the enucleated eyes.
Results:
One patient showed a choroidal melanoma with a primary non-Hodgkin lymphoma located solely in the affected eye. The other patient showed a systemic non-Hodgkin lymphoma with ocular manifestations concomitant with a choroidal melanoma.
Conclusions:
In the presence of yellow creamy infiltrates one should include a choroidal lymphoma in the differential diagnosis even if there is another clear pathologic condition. Furthermore in those cases systemic disease should be excluded.
