Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Attention deficit and hyperactivity disorder disrupts selective mechanisms of action.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2022

Same author

First-wave COVID-19 daily cases obey gamma law.

Infectious Disease Modelling·2022

Same author

Standardization of the psychometric hepatic encephalopathy score in a French population.

PloS one·2021

Same author

Measuring vergence and fixation disparity in 3D space.

The European journal of neuroscience·2020

Same author

Temporal representation impairment in developmental dyslexia for unisensory and multisensory stimuli.

Developmental science·2020

Same author

Commentary: Towards a unifying mechanism for cancelling movements.

Frontiers in psychology·2019

Search research articles

Related Experiment Video

Updated: May 20, 2026

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

Fall prevention modulates decisional saccadic behavior in aging.

Olivier A Coubard¹

¹The Neuropsychological Laboratory, CNS-Fed Paris, France.

Frontiers in Aging Neuroscience

|July 19, 2012

Summary

Fall prevention training improved saccadic control in older adults by enhancing motor responses and reducing variability. This suggests physical activity positively impacts central motor control processes.

Keywords:

aging eye movements motor activity motor control plasticity

More Related Videos

Behavioral Assessment of the Aging Mouse Vestibular System

Behavioral Assessment of the Aging Mouse Vestibular System

Published on: July 11, 2014

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Published on: October 25, 2024

Related Experiment Videos

Last Updated: May 20, 2026

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

Behavioral Assessment of the Aging Mouse Vestibular System

Behavioral Assessment of the Aging Mouse Vestibular System

Published on: July 11, 2014

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Published on: October 25, 2024

Area of Science:

Gerontology
Neuroscience
Motor Control

Background:

Aging populations experience increased fall frequency and motor decline.
Physical activity and skill learning benefit balance and reduce fall risk in older adults.
The impact of fall prevention programs on underlying motor control remains under-explored.

Purpose of the Study:

To investigate the effects of fall prevention (FP) training on saccadic control in older adults.
To analyze changes in saccade timing, dynamics, and underlying motor control processes.

Main Methods:

12 older adults (64-91 years) underwent 2.5 months of FP training.
Saccades were recorded before and after training.
Traditional saccade analysis and LATER model quantitative analysis were performed.

Main Results:

FP training reduced inappropriate anticipatory and express saccades, and increased appropriate express saccades.
Saccade latency decreased, and left-right symmetry of motor responses improved.
Within-participant variability in saccade duration, amplitude, and peak velocity was reduced.
LATER analysis indicated FP modulates decisional thresholds, with a new TIMER-RIDER model proposed.

Conclusions:

Fall prevention training positively influences saccadic control in older adults.
FP training enhances motor response efficiency and consistency.
The findings provide new insights into how motor training affects central motor control.