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Updated: May 20, 2026

Scoring Central Nervous System Inflammation, Demyelination, and Axon Injury in Experimental Autoimmune Encephalomyelitis
Published on: February 23, 2024
Changes in phospholipid composition of the spinal cord in rabbits with allergic encephalomyelitis as an experimental
E S Revina1, N V Gromova, T E Timoshina
1N. P. Ogarev Mordovian State University, Saransk, Russia.
Abstract:
Qualitative and quantitative composition of phospholipids in different compartments of the spinal cord was studied in normal rabbits and in experimental model of multiple sclerosis. The content of initial and final LPO products in compartments of the rabbit spinal cord was studied during different stages of the disease. The emergence of quantitative changes in the phospholipid composition depended on the form of experimental allergic encephalomyelitis and compartment of the spinal cord. The levels of conjugated dienes and MDA increased. The maximum levels of LPO products were recorded in the lumbar and sacral compartments of the spinal cord in severe experimental allergic encephalomyelitis.

