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10:45
Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Subcutaneous fungal infections
Ricardo M La Hoz1, John W Baddley
1Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Boulevard, Tinsley Harrison Tower 229, Birmingham, AL, 35294-0006, USA.
Current Infectious Disease Reports
|July 20, 2012
Summary
Subcutaneous mycoses like chromoblastomycosis, mycetoma, and sporotrichosis are common tropical infections. This review details their epidemiology, clinical presentation, diagnosis, and treatment.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Dermatology
Background:
- Subcutaneous mycoses are prevalent globally, particularly in tropical and subtropical zones.
- These fungal infections share common epidemiological traits, transmission routes, and clinical presentations.
- Characteristically, they present as indolent, chronic conditions with pyogranulomatous lesions, rarely disseminating in immunocompetent individuals.
Purpose of the Study:
- To consolidate current knowledge on three significant subcutaneous mycoses.
- To present updated data on the epidemiology, clinical features, diagnostic methods, and therapeutic strategies.
- To serve as a comprehensive resource for clinicians and researchers.
Main Methods:
- Systematic review of existing literature.
- Compilation of epidemiologic, clinical, diagnostic, and therapeutic information.
- Focus on chromoblastomycosis, mycetoma, and sporotrichosis.
Main Results:
- Detailed overview of the shared and distinct characteristics of chromoblastomycosis, mycetoma, and sporotrichosis.
- Emphasis on diagnostic challenges and evolving treatment protocols.
- Highlighting the importance of early and accurate diagnosis for effective management.
Conclusions:
- Subcutaneous mycoses require a thorough understanding of their multifaceted aspects for optimal patient outcomes.
- Integrated approach combining epidemiology, clinical presentation, and diagnostics is crucial.
- This review provides a vital update on managing these challenging fungal infections.
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