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Updated: May 20, 2026
09:49
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
[Neurologic disabilities after road traffic accidents]
1Médecine physique et réadaptation, Hôpital Raymond Poincaré, 92380 Garches. bernard.bussel@rpc.aphp.fr
Bulletin De L'Academie Nationale De Medecine
|July 21, 2012
Summary
Car accidents cause central nervous system damage, affecting mobility or cognition. Advances in understanding spinal cord and brain injuries improve patient outcomes and management strategies.
Area of Science:
- Neuroscience
- Neurology
- Traumatology
Context:
- Motor vehicle accidents are a significant cause of central nervous system (CNS) injuries.
- Spinal cord injuries (SCI) primarily result in locomotor and bladder dysfunction.
- Traumatic brain injuries (TBI) commonly lead to cognitive impairments.
Purpose:
- To review recent advancements in the management of CNS injuries.
- To highlight the impact of improved understanding of injury mechanisms on therapeutic strategies.
- To discuss the evolving approaches to treating locomotor disability and cognitive deficits.
Summary:
- Recent progress in understanding spinal cord injury mechanisms has led to new therapeutic solutions, reducing mortality and morbidity associated with locomotor and bladder dysfunction.
- Cognitive impairments following traumatic brain injury are now better characterized, leading to more efficient management strategies.
- Changes in the management of locomotor disability are driven by economic factors, philosophical shifts, and scientific progress.
Impact:
- Improved therapeutic interventions for spinal cord injury patients, leading to better functional recovery and reduced complications.
- Enhanced clinical management protocols for cognitive deficits post-TBI, improving patient quality of life.
- Significant reductions in mortality and morbidity associated with CNS injuries due to advancements in treatment and understanding.
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01:14Spinal Cord Injury ll: Pathophysiology
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