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Published on: February 17, 2018
Peripartum cardiomyopathy
Uri Elkayam1, Sawan Jalnapurkar, Mohamad Barakat
1Division of Cardiology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA. elkayam@usc.edu
Insights
Peripartum cardiomyopathy (PPCM) is a rare form of heart failure. Recent European guidelines update the definition of PPCM, improving diagnosis and management for pregnant women.
Area of Science:
- Cardiology
- Maternal Health
- Heart Failure
Background:
- Peripartum cardiomyopathy (PPCM) was first defined in 1971 by Demakis et al. based on specific clinical criteria.
- The original PPCM criteria are now recognized as arbitrary, and the condition can manifest earlier in pregnancy.
- A European Society of Cardiology working group has recently updated the definition of PPCM.
Purpose of the Study:
- To discuss the updated definition, causes, clinical presentation, prognosis, and treatment of peripartum cardiomyopathy (PPCM).
- To provide a comprehensive overview of PPCM, including related aspects.
Main Methods:
- Review and synthesis of existing literature and guidelines.
- Discussion based on the European Society of Cardiology's updated PPCM working group criteria.
- Exploration of etiological factors, clinical manifestations, and therapeutic strategies.
Main Results:
- The definition of PPCM has been refined to better capture earlier presentations and arbitrary criteria.
- The article covers the multifaceted aspects of PPCM, from etiology to management.
Conclusions:
- Updated diagnostic criteria for PPCM are crucial for timely and accurate diagnosis.
- Comprehensive understanding and management of PPCM are essential for improving maternal and cardiac outcomes.
- Further research into PPCM etiology and treatment is warranted.
Abstract:
In 1971, Demakis and colleagues established the term peripartum cardiomyopathy (PPCM) and defined it by criteria based on the clinical profile of their patients. With the recognition that these criteria are arbitrary and that PPCM often presents earlier in pregnancy, the definition of PPCM has been recently updated by a working group on PPCM of the European Society of Cardiology. This article discusses the cause, clinical presentation, prognosis, and treatment of PPCM, as well as other related topics.
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