Related Experiment Video
Updated: May 20, 2026

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
Published on: March 12, 2020
Prevention of postpneumonectomy syndrome in children with prophylactic tissue expander insertion
Lydia Choi1, Michael P LaQuaglia, Peter G Cordeiro
1Karmanos Cancer Center, Wayne State University, Detroit, MI, USA.
Insights
Prophylactic tissue expanders may prevent postpneumonectomy syndrome (PPS) in children. This study found tissue expander insertion safe and effective in pediatric patients undergoing pneumonectomy.
Area of Science:
- Pediatric Surgery
- Thoracic Surgery
- Surgical Complications
Background:
- Postpneumonectomy syndrome (PPS) is a serious complication following lung removal, affecting up to 15% of children.
- Children experience higher rates of PPS than adults due to their more elastic tissues.
Purpose of the Study:
- To evaluate the safety and efficacy of prophylactic tissue expander insertion in pediatric patients after pneumonectomy.
- To determine if tissue expanders can prevent postpneumonectomy syndrome in children.
Main Methods:
- A case series of 4 pediatric patients who underwent immediate prophylactic tissue expander insertion post-pneumonectomy.
- Monitoring for complications such as infection and evaluating the effectiveness of the tissue expanders in preventing PPS.
Main Results:
- Tissue expander insertion was successful in preventing PPS in all 4 patients.
- No infections occurred. One patient experienced tissue expander rupture, but a capsule had formed, negating the need for replacement.
Conclusions:
- Prophylactic tissue expander insertion appears to be a safe and potentially effective strategy for preventing PPS in pediatric patients.
- The benefits of preventing PPS must be weighed against the risks and procedural burden on a case-by-case basis.
Introduction:
Postpneumonectomy syndrome (PPS) is an often life-threatening complication of pneumonectomy that occurs in up to 15% of children. This occurrence is higher than in adults, presumably because of more elastic tissues in younger patients.
Methods:
We present a case series of 4 pediatric patients at Memorial Sloan Kettering Cancer Center, in whom prophylactic tissue expanders were inserted immediately after pneumonectomy.
Results:
Insertion of the tissue expander and prevention of PPS was successful in all patients. The presence of the tissue expander did not result in infection in any patient. Our only complication was rupture of the tissue expander in 1 patient, but by the time of removal, a capsule had already formed within the lung and replacement was unnecessary.
Conclusion:
This case series, although limited in number and follow-up, presents evidence that prophylactic tissue expander insertion appears to be a safe option for children requiring pneumonectomy. Its insertion at the time of pneumonectomy may prevent the devastating complications of PPS. Because it may result in a higher total number of procedures, the benefits must be weighed against the risks of insertion and decisions made for individual patients on a case-by-case basis.
Related Concept Videos
Pneumothorax-II
Clinical Manifestations:
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Cardiomyopathy VII: Pre and Post Operative Nursing Management