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Updated: May 20, 2026

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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Single-center experience using the Freedom SOLO aortic bioprosthesis.
Dimitrios C Iliopoulos1, Aris Rezar Deveja, Vasiliki Androutsopoulou
1Laboratory of Experimental Surgery and Surgical Research, University of Athens, Athens, Greece.
The Journal of Thoracic and Cardiovascular Surgery
|July 24, 2012
Summary
The Freedom SOLO stentless aortic valve demonstrated excellent early and intermediate-term outcomes in 128 patients undergoing aortic valve replacement. This study highlights its safety and efficacy, showing high survival rates and favorable hemodynamic performance.
Area of Science:
- Cardiovascular Surgery
- Bioprosthetic Valves
- Aortic Valve Replacement
Background:
- The Freedom SOLO stentless aortic bioprosthesis is utilized for aortic valve replacement.
- Assessing the performance of novel bioprosthetic valves is crucial for improving patient outcomes.
Purpose of the Study:
- To review the single-institution experience with the Freedom SOLO stentless aortic bioprosthesis.
- To evaluate the early and intermediate-term clinical and hemodynamic results of the Freedom SOLO valve.
Main Methods:
- A cohort of 128 patients underwent aortic valve replacement with the Freedom SOLO valve between 2006 and 2010.
- Follow-up was 100% complete at a mean of 36.7 months.
- Clinical outcomes, echocardiographic data, and survival rates were analyzed.
Main Results:
- The mean age of patients was 75.8 years, with a mean EuroSCORE of 9 ± 2.7.
- Perioperative mortality was 4.6%, with 36-month survival rates of 95.4% (low EuroSCORE) and 88.6% (high EuroSCORE).
- Significant reductions in transvalvular gradients and left ventricular end-diastolic diameter were observed postoperatively, with minimal aortic regurgitation.
Conclusions:
- The Freedom SOLO stentless aortic valve demonstrates excellent early and intermediate-term clinical and hemodynamic results.
- The valve is associated with favorable survival rates and low rates of complications.
- This study supports the use of the Freedom SOLO valve in patients undergoing aortic valve replacement.

