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Updated: May 20, 2026

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
Published on: October 3, 2025
The pathophysiology of uterine adenomyosis: an update
Giuseppe Benagiano1, Marwan Habiba, Ivo Brosens
1Department of Gynecology, Obstetrics and Urology, Sapienza, University of Rome, Rome, Italy.
Abstract:
The diagnosis of adenomyosis using noninvasive techniques such as vaginal ultrasounds and magnetic resonance has clear clinical applications and has renewed the interest in the pathogenesis of uterine adenomyosis. However, the research remains hampered by the lack of consensus on the classification of lesions. Magnetic resonance imaging and transvaginal ultrasound have comparable diagnostic accuracy. Minimal interventional biopsy techniques have recently been introduced. This article reviews human and animal studies and provides an update on the pathophysiology of adenomyosis. Recent views on the pathogenesis and links with endometriosis are discussed.
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