Related Experiment Video
Updated: May 20, 2026

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
Published on: September 17, 2021
Prolonged spasm of the left anterior descending coronary artery
Mehmed Kulic1, Elnur Tahirovic, Anes Sosevic
1Heart Center, Clinical Center University of Sarajevo, Bosnia and Herzegovina. kulicm@gmail.com
Insights
Prolonged coronary artery spasm, specifically in the left anterior descending artery, can cause cardiac arrest. Prompt cardiopulmonary resuscitation successfully restored the patient
Area of Science:
- Cardiology
- Clinical Medicine
Background:
- Coronary artery spasm is a recognized cause of anginal chest pain.
- Spasm can lead to serious cardiac events.
Observation:
- A case of prolonged left anterior descending coronary artery spasm occurred during coronary angiography.
- This event resulted in cardiac arrest, characterized by pulselessness, hypotension, syncope, and ventricular fibrillation on ECG.
Findings:
- Successful cardiopulmonary resuscitation lasting one hour restored normal pulse and blood pressure.
- Immediate repeat coronary angiography revealed a normal coronary angiogram, indicating the spasm was transient.
Implications:
- This case highlights the potential for severe, transient coronary artery spasm during invasive procedures.
- It underscores the importance of prompt recognition and resuscitation in managing such critical events.
- Patients can recover without neurological deficits following successful resuscitation from spasm-induced cardiac arrest.
Abstract:
Coronary artery spasm is one of the well-known causes of anginal chest pain. We presented the case of prolonged spasm of the left anterior descending coronary artery which happened during coronary angiography leading to pulse less state and low blood pressure with syncope and appearing of ventricular fibrillation on ECG. During one hour of successful cardiopulmonary resuscitation, the patient had again normal pulse and blood pressure. Coronary angiography performed immediately after DC's showed normal coronary angiogram. After two days the patient left the hospital without brain disorders.
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease III: Clinical Manifestations
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Cardiac Catheterization III: Left Heart Catheterization
Mitral Stenosis I: Introduction
