Related Experiment Video
Updated: May 20, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Interventional catheterization after total cavopulmonary connection: experience in 68 patients
Gabriella Agnoletti1, Roberto Bordese, Antonella Corleto
1Department of Paediatric Cardiology, O.I.R.M.-S. Anna Hospital, Turin, Italy. gabriella.agnoletti@oirmsantanna.piemonte.it
Nearly half of patients undergoing total cavopulmonary connection (TCPC) require interventions for complications like stenoses or shunts. Further research is needed to identify at-risk populations for improved outcomes after TCPC surgery.
Area of Science:
- Cardiology
- Pediatric Surgery
- Interventional Cardiology
Background:
- Total cavopulmonary connection (TCPC) is a surgical procedure for single-ventricle physiology, enabling pulmonary blood flow.
- Interventional catheterization is crucial for managing residual defects and complications post-TCPC.
Purpose of the Study:
- To evaluate the mid-term outcomes of interventional catheterization in patients who underwent TCPC.
- To identify the types of interventions required and their success rates in this patient cohort.
Main Methods:
- Retrospective review of catheterization data from 68 patients who had TCPC between January 1995 and December 2010.
- Mid-term results assessed using angiography and/or CT scans.
Main Results:
- Sixty-nine catheterizations were performed in 53 patients; 49% required interventions.
- Common interventions included embolization of shunting vessels (28%), pulmonary artery stenting/reconnection (9%), and systemic vein stenting/recanalization (21%).
- Post-intervention oxygen saturation improved significantly (90.5% to 94.7%, P = 0.002).
Conclusions:
- 49% of patients remain in good condition post-TCPC, but many require late interventions.
- Interventions frequently address stenoses within the TCPC or right-to-left shunts.
- A multicenter program is recommended to identify patients at risk for complications.
Related Concept Videos
Cardiac Catheterization II: Right Heart Catheterization
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Cardiac Catheterization III: Left Heart Catheterization

