Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Superabsorbent polymer microparticles incorporating with crown ether for swelling-enhanced selective and rapid lithium capture.

Chemosphereยท2026
Same author

Effectiveness of 2 behavioral interventions for voluntary opioid dosage reduction in patients prescribed high-dosage opioids for chronic pain.

Painยท2026
Same author

National trends in prescription drug expenditures and projections for 2026.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacistsยท2026
Same author

Follow-Up Patterns at a Low-Threshold Mobile Medical Unit Providing Opioid Use Disorder Care in an Urban Setting: A Group-Based Trajectory Modeling Approach.

Research squareยท2026
Same author

Economic sustainability of a comprehensive care health service delivery model for medicaid eligible children with chronic conditions.

Healthcare (Amsterdam, Netherlands)ยท2026
Same author

The effectiveness and value of brensocatib for the treatment of non-cystic fibrosis bronchiectasis.

Journal of managed care & specialty pharmacyยท2026
Same journal

Prescription drug prior authorization: costs to pharmacies and physicians.

The American journal of managed careยท2026
Same journal

Combined pharmacotherapy and psychotherapy impact on opioid use disorder treatment.

The American journal of managed careยท2026
Same journal

The societal costs of food insecurity: implications for managed care strategies.

The American journal of managed careยท2026
Same journal

Availability of hospital financial assistance documents in non-English languages.

The American journal of managed careยท2026
Same journal

Real-world weight loss with injectable semaglutide vs dulaglutide for diabetes.

The American journal of managed careยท2026
Same journal

Social needs screening and supplemental benefits in Medicare Advantage.

The American journal of managed careยท2026
See all related articles

Related Experiment Video

Updated: May 20, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Patient safety-focused medication therapy management: challenges affecting future implementation.

Rowena J Dolor1, Andrew L Masica, Daniel R Touchette

  • 1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. rowena.dolor@duke.edu

The American Journal of Managed Care
|July 25, 2012
PubMed
Summary
This summary is machine-generated.

Implementing pharmacist-delivered medication therapy management (MTM) off-site reduced patient and provider participation. Integrating MTM services within primary care clinics during existing appointments, with familiar pharmacists, is recommended for future studies.

More Related Videos

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Related Experiment Videos

Last Updated: May 20, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Area of Science:

  • Clinical Pharmacy
  • Health Services Research
  • Primary Care

Background:

  • Pharmacist-delivered medication therapy management (MTM) interventions in primary care (PC) offer valuable lessons for future studies and clinical adoption.
  • Understanding implementation challenges is crucial for optimizing MTM service delivery.

Purpose of the Study:

  • To describe variations and challenges in patient recruitment, enrollment, MTM pharmacist visits, and telephone follow-up within a randomized trial.
  • To identify factors influencing participation and effectiveness of MTM interventions in primary care settings.

Main Methods:

  • A 3-arm randomized trial of MTM interventions was conducted across 3 health centers.
  • Post-study structured interviews were conducted with study personnel, clinical pharmacists, and investigators.
  • Data collection focused on recruitment, enrollment, MTM visits, telephone follow-up, and provider response.

Main Results:

  • Patients with complex medical conditions, transportation issues, or lacking family support were less likely to enroll.
  • MTM visits scheduled separately from existing appointments had higher cancellation/no-show rates.
  • Provider response to pharmacist recommendations was low, particularly when the provider was unfamiliar with the pharmacist.

Conclusions:

  • Off-site MTM implementation led to reduced patient and provider participation.
  • Integrating MTM services within primary care clinics during existing appointments is recommended.
  • Utilizing pharmacists familiar to primary care providers can improve engagement and effectiveness.