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Nummular dystrophic calcification of an Ahmed glaucoma valve in a child
Arif O Khan1, Hind Al-Katan, Deepak P Edward
1Division of Pediatric Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. arif.khan@mssm.edu
Insights
This case study describes the first instance of calcium deposits on an Ahmed glaucoma valve in a child with primary congenital glaucoma. These deposits were found on the dorsal plate of the glaucoma drainage device.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- Primary congenital glaucoma is a rare condition requiring surgical intervention.
- Glaucoma drainage devices, such as the Ahmed glaucoma valve, are used to manage intraocular pressure.
- Complications can arise from ophthalmic implants, necessitating further investigation.
Observation:
- A 4.5-year-old girl with primary congenital glaucoma presented with increased intraocular pressure despite a previously implanted Ahmed glaucoma valve.
- Surgical intervention revealed multiple nummular calcium deposits on the dorsal plate of the Ahmed glaucoma valve.
- Histopathological examination and X-ray microanalysis confirmed the presence of calcium deposits.
Findings:
- This is the first reported case of calcium deposits specifically on an Ahmed glaucoma valve.
- The calcium deposits were located on the dorsal plate of the device.
- The presence of these deposits did not appear to be directly related to the initial failure of the device.
Implications:
- The findings suggest that calcium deposition is a potential, previously undescribed complication of glaucoma drainage devices.
- Further research is warranted to understand the mechanism and clinical significance of calcium deposits on glaucoma valves.
- This observation may inform the design and material selection for future ophthalmic implants.
Abstract:
We report the case of an otherwise-healthy 4.5-year-old girl with primary congenital glaucoma who had multiple nummular calcium deposits on the dorsal plate of a previously-implanted Ahmed glaucoma valve. The child had received the implant in the right eye at 6 months of age and developed increased intraocular pressure requiring surgical excision of surrounding fibrous encapsulation. Intraoperative inspection revealed that the dorsal plate surface was covered with multiple white nummular lesions; staining and X-ray microanalysis confirmed the lesions to be calcium deposits. Calcium deposits have been documented for various ophthalmic implants, including silicone scleral buckles and intraocular lenses, but to the best of our knowledge they have not previously been described in association with a glaucoma drainage device.
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