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A feasibility analysis of implementing interventions for discordant couples in 14 African countries: implications
1Center for Biomedical Modeling, Semel Institute of Neuroscience & Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA.
Abstract:
We find interventions targeting serodiscordant couples (SDC) may not be feasible in countries where HIV prevalence is less than 5%, because only 3-19/1000 individuals are HIV-positive/negative and in SDC. Interventions may be feasible in countries where prevalence is greater than 10%, because 34-48/1000 individuals are HIV-positive/negative and in SDC. We calculated that 20-27% of all HIV-positive individuals, but less than 6% of all HIV-negative individuals, are in SDC. Consequently, targeting HIV-positive partners could significantly reduce transmission, whereas targeting HIV-negative partners may have little impact.
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