Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders
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Updated: Jul 2, 2025

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
Published on: June 26, 2013
Janet Song1, Mauricio Castaño Ramírez2, Justin T Okano3
1Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Insights
Geographic access to mental healthcare in Colombia is unequal. Long travel times disproportionately affect outpatient access, highlighting the need to address healthcare inequities, especially in identified patient hotspots.
Area of Science:
- Mental Health Research
- Health Services Research
- Spatial Epidemiology
Background:
- Geographic variations in mood and psychotic disorders are documented in high-income nations.
- This study investigates geographic variations in these disorders within Colombia, a middle-income country.
- Analysis utilizes electronic health records from Clínica San Juan de Dios Manizales (CSJDM), serving one million inhabitants of Caldas.
Purpose of the Study:
- To examine geographic variations in mood and psychotic disorders in Colombia.
- To assess the relationship between travel time to a mental healthcare facility and disorder incidence.
- To identify potential disparities in access to mental health services.
Main Methods:
- Constructed a friction surface map of Caldas to calculate travel times to CSJDM.
- Analyzed travel times for 16,295 patients diagnosed with mood or psychotic disorders.
- Utilized zero-inflated negative binomial regression and spatial scan statistics to analyze incidence and identify patient clusters.
Main Results:
- Approximately 50% of the population has travel times under 1 hour to CSJDM, while 10% face over 4 hours.
- A significant distance-decay relationship was observed for outpatients (RR=0.80), with a 20% decrease in cases per hour increase in travel time.
- No distance-decay relationship was found for inpatients.
- Nine distinct clusters or hotspots of inpatient cases were identified.
Conclusions:
- The findings reveal healthcare access inequities, with long travel times potentially hindering outpatient treatment.
- Targeting resources to identified hotspots could improve identification of severely ill individuals.
- Further investigation into the factors contributing to these hotspots is warranted to address treatment disparities.
Background:
Geographical variations in mood and psychotic disorders have been found in upper-income countries. We looked for geographic variation in these disorders in Colombia, a middle-income country. We analyzed electronic health records from the Clínica San Juan de Dios Manizales (CSJDM), which provides comprehensive mental healthcare for the one million inhabitants of Caldas.
Methods:
We constructed a friction surface map of Caldas and used it to calculate the travel-time to the CSJDM for 16,295 patients who had received an initial diagnosis of mood or psychotic disorder. Using a zero-inflated negative binomial regression model, we determined the relationship between travel-time and incidence, stratified by disease severity. We employed spatial scan statistics to look for patient clusters.
Results:
We show that travel-times (for driving) to the CSJDM are less than 1 h for ~50% of the population and more than 4 h for ~10%. We find a distance-decay relationship for outpatients, but not for inpatients: for every hour increase in travel-time, the number of expected outpatient cases decreases by 20% (RR = 0.80, 95% confidence interval [0.71, 0.89], p = 5.67E-05). We find nine clusters/hotspots of inpatients.
Conclusions:
Our results reveal inequities in access to healthcare: many individuals requiring only outpatient treatment may live too far from the CSJDM to access healthcare. Targeting of resources to comprehensively identify severely ill individuals living in the observed hotspots could further address treatment inequities and enable investigations to determine factors generating these hotspots.
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