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Regional anesthesia.

P H LeBlanc1

  • 1Department of Large Animal Clinical Sciences, Michigan State University, College of Veterinary Medicine, East Lansing.

The Veterinary Clinics of North America. Equine Practice
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

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Local anesthetic agents are safe for horses, with rare organ toxicity. Complications typically arise from overdosage, which is uncommon due to the high dose required in horses, making them suitable for equine practice.

Area of Science:

  • Veterinary Anesthesiology
  • Equine Pharmacology

Background:

  • Organ toxicity from local anesthetic agents is infrequent.
  • Local anesthetics are considered safe for high-risk patients.
  • Complications are primarily linked to overdosage.

Purpose of the Study:

  • To evaluate the safety and efficacy of local anesthetic agents in equine practice.
  • To highlight the low incidence of adverse effects in horses.

Main Methods:

  • Review of complications associated with local anesthetic overdosage.
  • Analysis of systemic and neurological signs of toxicity.
  • Dose-response assessment in equine models.

Main Results:

  • Epidural overdosage can lead to motor paralysis and hind-limb weakness.

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  • Systemic signs include CNS changes, tremors, and hypotension.
  • A high dose (12 mg/kg) is required to induce these effects in horses, making overdosage rare.

    • Conclusions:

    • Local anesthetic techniques are attractive in equine practice due to a low side-effect profile.
    • The rarity of toxicity and low cost support their use in horses.
    • Careful dosage is essential to prevent complications.