Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Cyclic-AMP binding proteins in the head and neck.

D M Watson¹, J A Wilson

¹Department of Surgery, Royal Infirmary, Edinburgh, UK.

Clinical Otolaryngology and Allied Sciences

|October 1, 1990

Summary

This study measured cyclic adenosine monophosphate (cAMP) binding activity in head and neck tissues. A subgroup of parotid adenomas showed increased cAMP binding, suggesting a complex role in tumor growth.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Metrics of progress in the understanding and management of threats to Australian birds.

Conservation biology : the journal of the Society for Conservation Biology·2018

Same author

Factors associated with prophylactic plasma transfusion before vascular catheterization in non-bleeding critically ill adults with prolonged prothrombin time: a case-control study.

British journal of anaesthesia·2012

Same author

Application of sensory and instrumental volatile analyses to dairy products.

Annual review of food science and technology·2011

Same author

A national clinical scenario-based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients.

Transfusion medicine (Oxford, England)·2010

Same author

Germanium:gallium photoconductors for far infrared heterodyne detection.

Applied optics·2010

Same author

Sickness absence in industry.

The British journal of physical medicine : including its application to industry·2010

Area of Science:

Biochemistry
Oncology
Head and Neck Surgery

Background:

Cyclic adenosine monophosphate (cAMP) is a crucial second messenger involved in various cellular processes.
Understanding the role of cAMP binding proteins in head and neck cancers is essential for therapeutic development.

Purpose of the Study:

To investigate the levels of cAMP binding activity in diverse head and neck tissues.
To explore potential correlations between cAMP binding protein levels and specific tumor types, such as parotid adenomas.

Main Methods:

Quantitative analysis of cAMP binding activity.
Assessment of 34 tissue specimens from various head and neck anatomical sites.

Main Results:

A broad spectrum of cAMP binding protein levels was observed across all assessed head and neck tissues.
A distinct subgroup of parotid adenomas exhibited elevated cAMP binding activity compared to other tissues.

Conclusions:

The levels of cAMP binding proteins vary significantly within head and neck tissues.
Increased cAMP binding activity in parotid adenomas warrants further investigation into its biological significance and complex relationship with tumor progression.

Related Experiment Videos