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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
259
Does rapid maxillary expansion induce adverse effects in growing subjects?
Roberta Lione1, Lorenzo Franchi, Paola Cozza
1Department of Orthodontics, University of Rome, Rome, Italy.
The Angle Orthodontist
|July 26, 2012
Summary
Rapid maxillary expansion (RME) consistently opens the midpalatal suture in growing individuals. Long-term effects show tooth uprighting without compromising periodontal structures.
Area of Science:
- Orthodontics
- Craniofacial Growth
- Dental Research
Background:
- Rapid maxillary expansion (RME) is a common orthodontic procedure.
- Concerns exist regarding potential adverse effects of RME on craniofacial structures.
Purpose of the Study:
- To evaluate the scientific evidence on adverse effects of RME.
- Focus on midpalatal suture, vertical dimension, and dentoalveolar/periodontal structures in growing subjects.
Main Methods:
- Systematic literature search of electronic databases up to December 2011.
- Quality assessment of included studies using a 13-point scale.
Main Results:
- Thirty articles were reviewed; study quality varied, with most being low to medium.
- RME consistently opened the midpalatal suture (1.6-4.4 mm).
- Transient minor maxillary inferior movement and increased tooth tipping/alveolar bone bending were observed during active RME; long-term facial growth and dentoalveolar structures were unaffected.
Conclusions:
- RME effectively opens the midpalatal suture in growing patients.
- Observed vertical changes are minimal and temporary.
- Long-term follow-up indicates tooth uprighting and no compromise to periodontal health.
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