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Updated: May 20, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Thyroidectomy decreases snoring and sleep apnea symptoms
Alexandra E Reiher1, Haggi Mazeh, Sarah Schaefer
1Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, Wisconsin 53792-3284, USA.
Thyroid surgery significantly improves obstructive sleep apnea (OSA) symptoms in patients with goiter. This study shows reduced snoring and daytime sleepiness after thyroidectomy, highlighting the link between thyroid disease and sleep apnea.
Area of Science:
- Otolaryngology
- Endocrinology
- Sleep Medicine
Background:
- Goiter can cause compressive symptoms potentially leading to obstructive sleep apnea (OSA).
- The direct impact of thyroid enlargement on OSA symptoms remains unclear.
- Investigating the resolution of sleep apnea symptoms post-thyroidectomy is crucial.
Purpose of the Study:
- To evaluate the improvement in obstructive sleep apnea symptoms after thyroidectomy.
- To assess the efficacy of surgical intervention for thyroid enlargement in mitigating sleep-related breathing disorders.
Main Methods:
- Utilized the validated Berlin Questionnaire to assess sleep apnea risk before and 8 weeks after thyroidectomy.
- Administered questionnaires to patients experiencing snoring symptoms at a single academic institution.
- Analyzed questionnaire data to determine changes in OSA risk categories and symptom severity.
Main Results:
- 71% of patients screened high risk for OSA pre-surgery, decreasing to 51% post-surgery (p=0.002).
- Significant improvements observed in overall OSA scores (p<0.0001), snoring frequency (p=0.002), snoring bothersomeness (p=0.004), and daytime sleepiness (p=0.02).
- Higher preoperative thyrotropin levels were associated with less improvement in OSA symptoms.
Conclusions:
- Thyroidectomy appears to significantly alleviate obstructive sleep apnea symptoms in patients with pre-existing OSA risk.
- Clinicians should consider evaluating thyroid disease in patients presenting with OSA symptoms.
- Thyroid surgery offers a potential therapeutic avenue for improving sleep apnea in affected individuals.
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