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Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: May 20, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

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Published on: February 15, 2022

Ocular surface disease exacerbated glaucoma: optimizing the ocular surface improves intraocular pressure control.

Ruchika Batra¹, Rajen Tailor, Shabbir Mohamed

¹University Hospitals Birmingham, Birmingham, UK.

Journal of Glaucoma

|July 26, 2012

Summary

Treating ocular surface disease (OSD) in patients with primary open angle glaucoma can improve intraocular pressure (IOP) control. This approach may help manage glaucoma refractive to standard medical therapy.

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Ultrasound Cyclo Plasty in Eyes with Glaucoma

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Last Updated: May 20, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

Ophthalmology
Glaucoma Research
Ocular Surface Disease Management

Background:

Primary open angle glaucoma (POAG) management can be challenging in patients with co-existing ocular surface disease (OSD).
Severe OSD can render glaucoma medically refractory and compromise surgical outcomes.
The proposed condition, 'OSD exacerbated glaucoma,' highlights this complex interplay.

Purpose of the Study:

To describe a combination treatment approach for OSD in patients with inadequately controlled POAG.
To evaluate the impact of OSD management on intraocular pressure (IOP) control in these patients.

Main Methods:

Retrospective review of 4 patients with POAG and OSD.
Implemented combination OSD management: lid hygiene, oral doxycycline, topical carmellose sodium, and preservative-free glaucoma medications.
Patients were monitored for up to 24 months.

Main Results:

All patients showed significant symptomatic and clinical improvement in ocular surface health.
Observed reductions in ocular hyperemia, meibomian gland dysfunction, and superficial keratopathy.
Achieved a reduction in IOP in all patients, avoiding glaucoma drainage surgery.

Conclusions:

Aggressive management of OSD can improve IOP control in POAG patients.
Combination therapy for OSD is a viable strategy for 'OSD exacerbated glaucoma.'
This approach may enhance glaucoma management and reduce the need for further surgical intervention.