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Related Concept Videos

RNA Structure01:19

RNA Structure

The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic acids02:43

Nucleic acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...

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Related Experiment Video

Updated: May 20, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Folding RNA/DNA hybrid duplexes.

Ronny Lorenz1, Ivo L Hofacker, Stephan H Bernhart

  • 1Institute for Theoretical Chemistry, University of Vienna, Vienna, Austria. ronny@tbi.univie.ac.at

Bioinformatics (Oxford, England)
|July 26, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a new tool for predicting RNA/DNA hetero-dimer structures, addressing a gap in bioinformatics software. The enhanced ViennaRNA Package facilitates the study of these important biological molecules.

Related Experiment Videos

Last Updated: May 20, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • Existing bioinformatics tools primarily focus on predicting RNA or DNA secondary structures.
  • A significant gap exists in readily available software for predicting RNA/DNA hetero-dimer structures.
  • This limitation may contribute to the underreporting of biologically relevant RNA/DNA hetero-dimers.

Purpose of the Study:

  • To develop and present an extension for predicting RNA/DNA hetero-dimer structures.
  • To provide a user-friendly tool for researchers studying RNA/DNA interactions.

Main Methods:

  • Extension of the established ViennaRNA Package.
  • Incorporation of algorithms for hetero-dimer structure prediction.

Main Results:

  • Successful development of a novel RNA/DNA hetero-dimer structure prediction tool.
  • The tool is integrated into the widely recognized ViennaRNA Package.

Conclusions:

  • The presented extension fills a critical need in bioinformatics for RNA/DNA hetero-dimer analysis.
  • This tool is expected to accelerate the discovery and characterization of biologically relevant RNA/DNA hetero-dimers.